openCDMS evolved out of PsyGrid, an e-Science project funded by the Medical Research Council and the Department of Health. The aims of the PsyGrid project were to track a very large cohort of schizophrenia suffers from their first episode of psychosis and to develop the applications/middleware required to conduct wide-area epidemiology on this scale. The project has received further funding from the UK Mental Health Research Network and the National Institute of Health Research to develop openCDMS as a complete system for data management of clinical studies and trials.
openCDMS is free software and licensed under the GNU LGPL v3.0 or later.
Development of openCDMS began in May 2005 at the University of Manchester, and it has been in continuous development ever since, clocking up 15 years of developer time. The core team at the University of Manchester continue to develop and maintain the openCDMS code base, as well as hosting and operating openCDMS systems for UK medical research organisations. openCDMS has been deployed in a production environment since June 2006 and is a proven, reliable and robust system. Future developments planned for openCDMS can be found in the roadmap.